Skip to content

Grandview Children’s Centre is a supporter of discovery and innovation in research in child development and rehabilitation science. Our Research & Innovation Committee identifies priority areas for research and advises where our resources and/or support should be directed.

Grandview’s Research & Innovation Committee:

  • Chair: Dr. Carolyn Hunt, Medical Director, Developmental Pediatrician
  • Emma Delemere, Behavioural Consultant
  • Lindsay Gurr, Physiotherapist
  • Janet Isaac, Clinical Manager
  • Karen Jagne, Communicative Disorders Assistant
  • Angela Kielbowski, CPNET and ACSF:SC Research Assistant
  • Dr. Shannon Knights, Developmental Pediatrician
  • Sarah Lee, Communicative Disorders Assistant
  • ex officio: Leslie Suite, Speech-Language Pathologist & Director of Clinical Services
  • ex officio: Lorraine Sunstrum-Mann, Chief Executive Officer
  • Recorder: Jackie Down, Medical Services Assistant

Read our RESEARCH PORTFOLIO 2017-2022 for a complete list of all our projects.

Please note:

GrandviewKids is only directly involved in the CPNET, CP PAIN and ACSF:SC Studies. Recruitment for the other studies occurs off-site. Each study has been approved by the GrandviewKids Research and Innovation Committee.  If you would like us to share your research project, please complete the GrandviewKids Application for Approval of a Research Study and send it to research.committee@grandviewkids.ca

 

Stimulation for Perinatal Stroke – Optimizing Recovery Trajectories (SPORT Study)

 

Who can participate?

  • Age 6–18 years
  • Clinical and MRI-confirmed perinatal ischemic stroke (NAIS, APPIS, PVI)
  • Symptomatic hemiparetic CP including child/parent perceived limitations in function with disability severity that allows lifting the affected arm above a table surface and some ability to grasp light objects

What’s involved?

  • A 2-week summer camp, 5 days a week from 9am-4pm
    • Be randomly assigned to either the intervention (tDCS) group or the control (sham) group (50/50 chance)
    • Wear a watch on each wrist to see how much you move your hands and arms during the camp.
    • Engage in activities that involve using your hands with the research OT 4 times through the duration of the study (about 3-4 hours each session)
    • You will be asked to answer some questions about your home and school life, as well as your overall experience in the camp (about 30-60 mins)
    • If able (i.e., you have no metal in your body including braces, metal rods, plates, screws, nails, wire, or an electric implant or device), MRI pictures of your brain taken at 3 different time points (1 hour per session) at SickKids

Exclusion Criteria:

  • Other neurological disorder not related to perinatal stroke
  • Multifocal stroke
  • Severe hemiparesis (MACS V)
  • Severe spasticity (Modified Ashworth Scale >3)
  • Severe delay or inability to comply with protocol
  • Unstable epilepsy
  • Any TMS or MRI contraindication
  • Orthopaedic surgery, constraint, brain stimulation or other modulatory therapy in past 6 months.
  • Botox in the past 4 months

 

Understanding Pain Trajectories and Their Association with Well-being in Children and Youth with Cerebral Palsy

What’s involved?

•       If you/your child participate, you/your child will be asked to complete questionnaires once a week for 6 weeks

•       The first meeting (baseline) will be at your treatment center & will last one hour

•       We will meet/email/phone you one time every week for five weeks (follow-ups 1 -5)

•       Four questionnaires emailed, mailed or over the phone (your choice) will take 5 minutes each (Follow-ups 1-4)

•       The last questionnaire emailed, mailed, by phone or in person at your treatment center (your choice) will take 30 minutes or less (Follow-up 5)

•       We will ask you questions about if you have any pain, what the pain is like, how it makes you feel and affects you.

•       Evening and weekend appointments are available

•       Participants will receive a $25 gift card as a thank you for their time

•       Volunteer hours for participation time

Who can participate?

We are looking for children and youth who:

1)    are 8 to 18 years old inclusive

2)    have been diagnosed with Cerebral Palsy (CP)

3)    can communicate with or without assistive devices

4)    can complete a sorting task

5)    are current or past clients of Holland Bloorview or Grandview treatment centres.

Why should you consider participating?

Your input will help us understand if and when you have pain, and how it makes you feel. You will help inform families, clinicians and researchers about how pain and well-being in children and youth with cerebral palsy changes over time.

Contact Information

If you are interested in participating in this study or have additional questions, please contact Heather Shearer at 416-425-6220 ext. 6597 (Toll free: 1-800-363-2440 ext. 6597), hshearer@hollandbloorview.ca or heather.shearer@grandviewkids.ca and she will get back to you shortly. Contacting us does not obligate you/your child to participate in the study.

We are inviting you and your child to take part in the Better Nights, Better Days for Children with Neurodevelopmental Disorders (BNBD-NDD) study! The purpose of the BNBD-NDD study is to evaluate the effectiveness of the online, eHealth program for parents of children with neurodevelopmental disorders who experience sleeping problems, including bedtime resistance, trouble settling to sleep, night waking, and early morning awakening.

Who can participate?

We are looking for parents of children ages 4 to 12 years old who have been diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD), Cerebral Palsy (CP), and Fetal Alcohol Spectrum Disorder (FASD) across Canada.

What’s involved?

•       If you participate, you will be asked to complete assessments at 3 periods: baseline, 4-month follow-up, and 8-month follow-up

•       At each assessment:

–      You will complete a Sleep Diary for 7 days

–      Your child will wear an actigraph (a watch-like device that measures sleep) for 7 days

–      You will answer a series of questionnaires about your child’s sleep, daytime behaviour, and the parent’s functioning

•       To thank you for your time and effort, you will receive $25 for each assessment period you complete, and a bonus $25 for completing all three assessments, for a potential total of $100

•       Interested families can enter the online study database to begin eligibility assessment at the following link: http://ndd.betternightsbetterdays.ca/

Why should you consider participating?

Your input will help us evaluate the effectiveness of the eHealth BNBD-NDD program designed specifically for parents of children with neurodevelopmental disorders.  The BNBD-NDD program is designed to teach parents skills to help improve their child’s sleep using behavioural techniques. This study may help provide accessible treatment to parents for childhood sleep problems and improve childhood insomnia in the future.

Contact Information

Sydney Dale-McGrath, BA, MA

Research Manager

bnbd-ndd@dal.ca

CPNET Research Flyer
CPNET Flyer

The CP-NET Research Database is an Ontario Brain Institute funded research project. We are collecting information to better understand how many kids are affected by Cerebral Palsy (CP) in different parts of Ontario and what causes CP so that we can improve care and treatments.

What’s involved?

Study participants will attend two research assessments, approximately 1-4 years apart. During the first assessment we will ask you questions about your family and medical history and your child’s experience with CP. We will collect saliva samples from you and your child. We will also ask to review your family’s medical charts and collect any past brain scans your child may have had. During both assessments, your child will be seen by a doctor who will examine his or her movements. Lastly, your child may be given a brief learning assessment during the second assessment.

Who can participate?

Children aged 2-7 years old, who have CP and live in certain regions of Ontario.

Why should you consider participating?

Your participation will enable researchers to study the causes of CP, identify risk factors and develop treatments and interventions to improve outcomes and care for children with CP. You will receive a $20 gift card to Chapters after the completion of each research assessment.

Contact Information

Angela Kielbowski
(905) 728-1673 ext. 2547

Information updated: August 29 2017
Study expires: December, 2023

 

We are inviting all parents, family members, and professionals who have direct contact with children/youth with autism to participate in a reliability study to test our easy to use tool of social communication ability, the Autism Classification System of Functioning: Social Communication (ACSF:SC-Integrated).

This tool classifies 5 Levels of social communication for children/youth with autism. It was originally developed for preschoolers (age 3 to <6 years), but we have now made some revisions to be used with toddlers (starting at 2 years of age) and school-aged children/youth (6 years and older).

 

What’s involved?

Participants will be asked to complete the following measures: the ACSF:SC rating for their child/youth, as well as the Demographics (2pages) and Thought Process questionnaire (5 pages). For each child/youth we will seek ratings at two time points (about 4 to 6 weeks apart) from a parent/guardian, for intra-rater reliability.   And we will seek a paired rating from a professional (e.g., clinician, therapist, educator, etc.) who knows the child/youth well.

Who can participate?

Parents/ guardians of children two years or older with autism.

Why should you consider participating?

Your participation will help researchers determine the validity of the ACSF:SC tool for a wider age range of children.  Study participants will receive a $20 gift card from Chapters/Coles/Indigo for each completed study package.

Contact Information

Helena Viveiros
(905) 525-9140 ext. 27849
viveiro@mcmaster.ca

 

Angela Kielbowski
(905) 728-1673 x2547
angela.kielbowski@grandviewkids.ca

 

Information updated: April 24, 2019
Study Expires: April 2020

 

 

Holland Bloorview Kids Rehabilitation Hospital Autism Research Centre and the POND-Network are currently conducting new research studies across Ontario to understand how genes and biology affect the brain and behaviour in Autism and other Neurodevelopmental Disorders.

What’s involved?

Please contact Susan Day Fragiadakis (see below) for detailed information on current studies.

Who can participate?

Children 21 years or younger who have a Neurodevelopmental disorder (e.g., ASD, Intellectual Disability, Rett Syndrome or Fragile X, Down Syndrome, Anxiety Disorder) and typically developing children between the ages of 3 – 21 years.

Why should you consider participating?

By participating you are helping researchers understand how genes affect the brain, body, and behavior, and then translate this understanding into new ways to help individuals with autism and associated neurodevelopmental disorders.

Contact Information

Susan Day Fragiadakis
(416) 425-6220 ext. 6518
sfragiadakis@hollandbloorview.ca

 

Information updated: August 29, 2017
Study expires: March 31, 2020

TIDE Research FlyerThe Autism Research Centre at Holland Bloorview Kids Rehabilitation Hospital is conducting a research study looking for young people (ages 12-17) with ASD. The overall goal of the study is to see if the medication tideglusib helps to improve symptoms of Autism Spectrum Disorder, specifically social engagement, social functioning (e.g. learning how to talk to others, making friends) and repetitive behaviours.

What’s involved?

The study lasts a total of 16 weeks (about 4 months) and involves taking the medication dissolved in water every day for three months, with a follow up visit one month later. You and your child will first be asked to come in for a screening session; through talking with you and completing some assessments we will determine if your child meets eligibility criteria. If your child meets criteria, you will then receive either tideglusib or placebo. Visits will take place every two weeks while your child is taking the drug or placebo. This study also has an optional continuation part, which means that if you were given placebo, you will be able to take tideglusib at the end of the four months. The same tests and procedures will be followed that were followed during the main study.

Who can participate?

Individuals aged 12-17 with Autism Spectrum Disorder who meet the eligibility criteria identified at the screening session.

Why should you consider participating?

Participation in this study will help researchers see if the medication tideglusib helps to improve symptoms of Autism Spectrum Disorder.

Contact Information

Naomi Peleg
(416) 425-6220 ext. 3456
npeleg@hollandbloorview.ca

 

Information updated: August 29, 2017
Study Expires:

Infant Sibling Research Flyer
Infant Sibling Poster

Researchers are trying to determine whether early behavioural signs of Autism Spectrum Disorder (ASD) can be observed in young infants. Second we hope to learn more about whether differences in certain body signals (such as temperature, heart rate, sweating) during a variety of tasks can be observed. We want to see if these signs are different in infants who go on to have ASD, compared to those who do not.

What’s involved?

We will use tests that look at the symptoms of autism, tests that look at the way that your child thinks and behaves, and activities that look at the way your child reacts. Your child will be seen for their first visit at 6 or 12 months based on their age at recruitment. Your child will be followed in 6 month intervals between 6 months and 24 months then at 36 months. Parent interviews and questionnaires will also be completed at these time points.

Who can participate?

Younger siblings (6-12 months of age) who have an older sibling with ASD OR younger siblings (6-12 months of age) who have an older sibling whose families do not have a history of ASD.

Why should you consider participating?

By participating you will receive ongoing feedback about your child’s development, have opportunities to ask questions about your child’s development and contribute to our understanding of autism.

Contact Information

Jessica Contini
(416) 425-6220 ext. 6352
jcontini@hollandbloorview.ca

 

Information updated: August 29, 2017
Study expires: December 2019

 

The purpose of this research is to see if motor skills, social skills and behavioural skills improve after a motor skill intervention.

What’s Involved?

The motor skill intervention is an instructional play-based program that will take place at the UOIT Physical Activity and Motor Behaviour lab and will be run by highly trained personnel as well as graduate and undergraduate Kinesiology students at UOIT. Children will receive 12 weeks of intervention for 2 hours/week. Children will be randomly assigned to either Group 1, which receives the intervention first, or Group 2, which receives the intervention second. Children will participate in 3 assessments and play dates in addition to the intervention sessions.

Who can participate?

Children aged 3-5 years old with Autism Spectrum Disorder (ASD).

Why should you consider participating?

By participating you will help researchers determine whether this motor-skill intervention improves motor, social and behavioural skills in children aged 3-5 with ASD.

Contact Information

For more information please contact:

Dr. Meghann Lloyd
Meghann.lloyd@uoit.ca.

 

The purpose of this research is to understand whether our employment intervention is useful for youth looking for jobs. We are comparing two different online employment programs—one with and the other without online peer mentoring.

What’s involved?

Participants will be asked to take part in an online discussion at least 3 times per week for 4 weeks (3 new topics each week) and complete a survey at the beginning and end of the program

Who can participate?

We are looking for:
• Youth with a physical disability, aged 15-25
• Able to read/write in English
• Currently enrolled in or recently completed high school in the applied / academic stream
• Have access to a computer and internet

Why should you consider participating?

Your participation will help researchers learn whether our employment readiness topics meet the needs of youth with disabilities. You will receive a gift card for participating and a letter for volunteer hours (if requested)

 

Contact Information

Elaine Cagliostro
ecagliostro@hollandbloorview.ca
(416) 425-6220 x6496

Some children and youth with cerebral palsy experience fatigue that impacts
their health and day-to-day life activities. At this time, we don’t know who is
most impacted by fatigue, and when fatigue becomes a problem, our study will
help us learn these things

What’s involved?

This study involves completing questionnaires online. Participants will be part
of the study for one year and will provide answers to questionnaires two
times. Each time it will take about 30-45 minutes to fill out the survey.
Participants in the research will receive a $15 electronic gift card to iTunes or
Chapters/Indigo (your choice) when you complete the second survey.
This study will run from July 2018 to December 2019.

Who can participate?

Eligible participants are those who:
• Have a diagnosis of Cerebral Palsy
• Are between 7 and 18 years old
• Speak English

 

Why Should You Consider Participating?

Knowing more information about fatigue experienced by youth with cerebral palsy will help researchers and therapists develop treatments for this condition.

 

Contact Information

Laura Brunton
lbrunto3@uwo.ca
(519) 661-2111 x81501

 

expires December 2019

We are inviting you and your child to take part in the National Physical Activity Measurement (NPAM) study! The purpose of the NPAM study is to measure current trends in physical activity, sleep, and screen-time behaviour among Canadian children and youth with disabilities.

Who can participate?

We are looking for Canadian children and youth (ages 4 to 17 years) with any type of disability and their parents to participate. Please note that at this stage in our study, children and youth with Autism Spectrum Disorder are not eligible to participate.

What’s involved?

• Children and youth will be asked to wear a Fitbit for 30 days, ideally for 24-hours a day.
• Youth (ages 10 to 17 years) will be asked to complete one, 45-minute telephone interview about their daily activities and well-being.
• Parents will be asked to complete a 30-minute online survey about their child’s daily activities and well-being.

Why should you consider participating?

Your input will help us understand the typical behaviours and well-being of children and youth with disabilities. This kind of information will help support the development of evidence-based policies and programs to better serve Canadian kids with disabilities.
Children and youth will have the opportunity to keep the Fitbit after wearing it for 30 days. Youth will receive 5 community service/volunteer hours for completing the interview. Parents will receive a $10 gift card of their choice for completing the online survey.

Contact Information

Ritu Sharma
ri.sharma@mail.utoronto.ca

The purpose of this study is to find out whether MEVU is a good tool for assessing how children with CP use vision.

What’s involved?

Researchers from Australian Catholic University are testing a new online questionnaire to describe how a child uses vision in everyday activities – the new ‘Measure of Early Vision Use’.
If you choose to participate, you will be asked to complete an online survey. There are some questions about you and your child, and the ‘Measure of Early Vision Use’ (MEVU) to complete. MEVU consists of 14 questions and should not take more than 10 minutes to answer, however completion of the entire survey may take up to 40 minutes depending on how many sections you complete. You may open the survey by clicking on the link provided here: http://j.mp/2Nbj4wK

Who can participate?

They are seeking parents and caregivers of children aged between 3 months and 12 years of age who have a diagnosis or high risk of developing cerebral palsy. Children with a range of visual abilities are being sought, from a good ability to use vision, to the ‘not so good’.

Why should you consider participating?

Vision is important to all areas of development and learning. If you are the parent or caregiver of a child with CP, taking part in this research will help establish a new measurement tool that may be used with other families in the future. We hope this may help more children in the future. Responses from parents in the testing phase (now!) are needed for that to happen.

Contact information

For more information please contact:
Belinda Deramore Denver
belinda.deramoredenver@myacu.edu.au

Physical activity improves social life, quality of life, and health. Some children and teens with physical disabilities, such as cerebral palsy do not try as many different activities as other youth. One reason might be that they have low balance confidence. Balance confidence is a person’s feelings about his or her balance during certain activities or settings. Right now, there is no reliable way to measure balance confidence in youth with cerebral palsy.

What’s involved?

  • Two sessions, one to two weeks apart at Holland Bloorview or in your home (it’s your choice)
  • Complete the new questionnaire at both sessions
  • At the first session, also complete four other measures: two that measure balance, one that measures physical abilities, and a physical activity questionnaire
  • Participants will be eligible for volunteer hours
  • To thank you for your participation, participants will receive a $20 gift card to Sport Chek or Indigo

Who can participate?

  • Children and teens with cerebral palsy who can walk without a walker or cane for at least a short distance indoors AND typically-developing children and teens
  • Ages 9 to 18 years inclusive

 

Contact information

If you are interested in participating in this study or have additional questions, please contact Megan Towns at 416-425-6220 ext. 3127 or mtowns@hollandbloorview.ca with your interest, and she will get back to your shortly. Contacting us does not obligate you or your child to participate in the study.

The purpose of this study is to assess the common and unique factors related to musical experiences, social development, and emotional well-being across diverse children and families. We will assess these factors in families of children with and without developmental, medical, or mental health needs. We are interested in the musical/arts experiences of the children, parents, and family as a whole.

What’s involved?

Parent responses to an online survey. Survey questions ask families about their general background, children’s musical experiences, parent-child relationship, parent’s musical experiences and well-being and children’s play interests.

Who can participate?

Parents of children 6 months to 5 years of age with or without ASD, developmental or language delay, neurodevelopmental genetic syndrome, or other health impairments. The goal is to collect online survey responses from 800 parents across Canada and the USA.

Contact information:

Access the survey at
https://is.gd/MusicChildrenFamilies